John H Alexander Selected Research

Warfarin (Coumadin)

1/2022	Heterogeneity of diabetes as a risk factor for major adverse cardiovascular events in anticoagulated patients with atrial fibrillation: an analysis of the ARISTOTLE trial.
1/2022	Apixaban or Warfarin and Aspirin or Placebo After Acute Coronary Syndrome or Percutaneous Coronary Intervention in Patients With Atrial Fibrillation and Prior Stroke: A Post Hoc Analysis From the AUGUSTUS Trial.
1/2022	Direct Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation: Patient-Level Network Meta-Analyses of Randomized Clinical Trials With Interaction Testing by Age and Sex.
1/2021	Premature permanent discontinuation of apixaban or warfarin in patients with atrial fibrillation.
1/2021	Individual Patient Data from the Pivotal Randomized Controlled Trials of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation (COMBINE AF): Design and Rationale: From the COMBINE AF (A Collaboration between Multiple institutions to Better Investigate Non-vitamin K antagonist oral anticoagulant use in Atrial Fibrillation) Investigators.
1/2021	Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Left Ventricular Hypertrophy: Insights From the ARISTOTLE Trial.
11/2020	Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve.
1/2020	Regional variation in clinical characteristics and outcomes in patients with atrial fibrillation: Findings from the ARISTOTLE trial.
1/2020	Patients With Atrial Fibrillation Taking Nonsteroidal Anti-Inflammatory Drugs and Oral Anticoagulants in the ARISTOTLE Trial.
1/2020	Effects of apixaban compared with warfarin as gain in event-free time - a novel assessment of the results of the ARISTOTLE trial.

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John H Alexander Research Topics

Disease

107	Atrial Fibrillation 01/2022 - 12/2008
99	Stroke (Strokes) 01/2022 - 04/2005
96	Hemorrhage 01/2022 - 01/2005
62	Myocardial Infarction 01/2022 - 04/2003
54	Acute Coronary Syndrome 01/2022 - 01/2004
40	Embolism (Embolus) 01/2022 - 03/2010
22	Heart Failure 01/2022 - 10/2011
14	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021 - 01/2006
11	Thrombosis (Thrombus) 01/2021 - 01/2005
10	Transient Ischemic Attack 01/2022 - 01/2014
9	ST Elevation Myocardial Infarction 11/2018 - 06/2004
8	Inflammation (Inflammations) 01/2022 - 04/2007
8	Cardiovascular Diseases (Cardiovascular Disease) 10/2021 - 11/2005
8	Type 2 Diabetes Mellitus (MODY) 09/2021 - 05/2010
7	Ischemic Stroke 12/2020 - 03/2010
6	COVID-19 01/2022 - 01/2020
6	Left Ventricular Dysfunction 01/2022 - 05/2013
6	Venous Thromboembolism 01/2021 - 01/2005
6	Diabetes Mellitus 01/2019 - 09/2012
6	Body Weight (Weight, Body) 01/2019 - 04/2005
5	Thromboembolism 01/2022 - 01/2005
5	Necrosis 01/2022 - 04/2008
5	Neoplasms (Cancer) 10/2020 - 01/2011
5	Chronic Renal Insufficiency 01/2020 - 11/2012
5	Cardiogenic Shock 01/2020 - 04/2007
4	Hyperplasia 01/2022 - 10/2005
4	Ischemia 12/2020 - 12/2004
4	Venous Thrombosis (Deep-Vein Thrombosis) 11/2020 - 01/2005
4	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2020 - 12/2013
4	Vascular Diseases (Vascular Disease) 01/2019 - 01/2014
4	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2016 - 09/2012
4	Hypertension (High Blood Pressure) 01/2016 - 12/2013
4	Infarction (Infarctions) 10/2009 - 12/2004
3	Sarcoma (Soft Tissue Sarcoma) 12/2021 - 10/2015
3	Mitral Valve Insufficiency (Mitral Regurgitation) 11/2021 - 01/2012
3	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 01/2019
3	Peripheral Arterial Disease 01/2021 - 01/2016
3	Pulmonary Embolism 11/2020 - 10/2009
3	Albuminuria 04/2020 - 01/2018
3	Kidney Diseases (Kidney Disease) 04/2020 - 01/2018
3	Hemorrhagic Stroke 01/2020 - 09/2011
3	Hypoglycemia (Reactive Hypoglycemia) 01/2020 - 01/2012
3	Hypersensitivity (Allergy) 12/2016 - 01/2016
3	Death (Near-Death Experience) 02/2015 - 01/2014
3	Wounds and Injuries (Trauma) 01/2011 - 06/2004

Drug/Important Bio-Agent (IBA)

97	apixabanIBA 01/2022 - 06/2009
68	Warfarin (Coumadin)FDA LinkGeneric 01/2022 - 03/2010
37	AnticoagulantsIBA 01/2022 - 01/2005
26	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022 - 06/2008
20	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2004
19	Vitamin K FDA Link 01/2022 - 03/2010
15	CreatinineIBA 01/2022 - 11/2008
9	Heparin (Liquaemin)FDA LinkGeneric 01/2021 - 06/2004
9	TroponinIBA 01/2020 - 11/2006
9	Factor Xa InhibitorsIBA 01/2020 - 01/2005
8	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2022 - 11/2014
8	Pharmaceutical PreparationsIBA 01/2021 - 12/2006
7	omega-Chloroacetophenone (Mace)IBA 01/2022 - 06/2013
7	LinagliptinIBA 09/2021 - 01/2018
7	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2021 - 08/2015
6	Troponin T (Troponin T1)IBA 01/2022 - 01/2014
6	Simendan (Levosimendan)IBA 01/2022 - 12/2016
6	pro-brain natriuretic peptide (1-76)IBA 01/2022 - 04/2016
6	CSL112IBA 01/2021 - 08/2015
6	Hemoglobins (Hemoglobin)IBA 01/2020 - 10/2014
6	RB 006IBA 12/2016 - 10/2011
6	Clopidogrel (Plavix)FDA Link 01/2016 - 06/2008
5	Cystatin CIBA 01/2022 - 11/2012
4	CalciumIBA 01/2022 - 04/2008
4	Factor Xa (Coagulation Factor Xa)IBA 01/2022 - 01/2005
4	Interleukin-6 (Interleukin 6)IBA 01/2022 - 04/2016
4	RivaroxabanIBA 01/2022 - 11/2020
4	fibrin fragment D (D-dimer)IBA 12/2021 - 01/2020
4	Growth Differentiation Factor 15IBA 11/2021 - 11/2014
4	AlbuminsIBA 01/2021 - 01/2018
4	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 01/2020 - 01/2018
4	Fibrinolytic Agents (Antithrombotic Agents)IBA 05/2017 - 04/2003
4	Troponin IIBA 02/2015 - 11/2006
4	Tenecteplase FDA Link 04/2005 - 04/2003
3	Thrombin Receptors (Thrombin Receptor)IBA 01/2022 - 01/2016
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2022 - 02/2014
3	Angiotensin Receptor AntagonistsIBA 01/2022 - 02/2014
3	Enoxaparin (Lovenox)FDA LinkGeneric 12/2021 - 06/2004
3	CholesterolIBA 01/2021 - 10/2016
3	N(4)-oleylcytosine arabinosideIBA 01/2021 - 01/2019
3	Creatine Kinase (Creatine Phosphokinase)IBA 12/2016 - 01/2006
3	MB Form Creatine KinaseIBA 12/2016 - 01/2006
3	Factor IXa (Coagulation Factor IXa)IBA 01/2016 - 06/2008
3	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2011 - 04/2003
3	edifoligideIBA 02/2008 - 10/2005

Therapy/Procedure

68	Therapeutics 01/2022 - 01/2004
27	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2022 - 02/2007
27	Percutaneous Coronary Intervention 01/2022 - 06/2004
6	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2022 - 04/2008
6	Drug Therapy (Chemotherapy) 01/2021 - 02/2014
5	Stents 01/2021 - 01/2018
5	Secondary Prevention 01/2018 - 03/2007
4	Thrombolytic Therapy 01/2011 - 06/2004
3	Limb Salvage 12/2021 - 01/2020
3	Orthopedic Procedures 07/2013 - 01/2005